Product overview:

Carrier-free (BSA/glycerol-free) RORC mouse monoclonal antibody,clone LBI3C12

Field of research:

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Summary:

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

NR1F3; RORG; RZR-GAMMA; RZRG; TOR

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RORC

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-266 of human RORC (NP_005051) produced in E.coli.

Clone:

LBI3C12

Conjugation:

Unconjugated

Gene name:

Homo sapiens RAR related orphan receptor C (RORC), transcript variant 1, mRNA.

Symbol:

RORC

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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