Product overview:

Carrier-free (BSA/glycerol-free) PGII mouse monoclonal antibody,clone LBI3C2

Field of research:

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Summary:

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]

Alternative names:

PEPC; PGII

Species reactivity:

Human

Host:

Mouse

Target:

PGC

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 17-388 of human PGII(NP_002621) produced in E.coli.

Clone:

LBI3C2

Conjugation:

Unconjugated

Gene name:

Homo sapiens progastricsin (PGC), transcript variant 1, mRNA.

Symbol:

PGC

Pathway:

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Function:

Protease, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

1:250 - 1:1000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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