Product overview:

Carrier-free (BSA/glycerol-free) FOXO3 mouse monoclonal antibody,clone LBI5F11

Field of research:

Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer

Summary:

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Alternative names:

AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FOXO3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 374-673 of human FOXO3 (NP_001446) produced in E.coli.

Clone:

LBI5F11

Conjugation:

Unconjugated

Gene name:

Homo sapiens forkhead box O3 (FOXO3), transcript variant 1, mRNA.

Symbol:

FOXO3

Pathway:

Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com