Product overview:

Carrier-free (BSA/glycerol-free) FTO mouse monoclonal antibody,clone LBI4A1

Field of research:

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Summary:

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

Alternative names:

ALKBH9; BMIQ14; GDFD

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FTO

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human FTO (NP_001073901) produced in HEK293T cell.

Clone:

LBI4A1

Conjugation:

Unconjugated

Gene name:

Homo sapiens FTO alpha-ketoglutarate dependent dioxygenase (FTO), transcript variant 3, mRNA.

Symbol:

FTO

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com