Product overview:

Carrier-free (BSA/glycerol-free) TGFBR3 mouse monoclonal antibody,clone LBI4F11

Field of research:

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Summary:

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2010]

Alternative names:

betaglycan; BGCAN

Species reactivity:

Human

Host:

Mouse

Target:

TGFBR3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 531-777 of human TGFBR3(NP_003234) produced in E.coli.

Clone:

LBI4F11

Conjugation:

Unconjugated

Gene name:

Homo sapiens transforming growth factor beta receptor 3 (TGFBR3), transcript variant 1, mRNA.

Symbol:

TGFBR3

Pathway:

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Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com