Product overview:

Carrier-free (BSA/glycerol-free) RING1 mouse monoclonal antibody,clone LBI2D11

Field of research:

Request info at info@sobekbio.com

Summary:

This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008]

Alternative names:

RING1A; RNF1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RING1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 88-362 of human RING1(NP_002922) produced in E.coli.

Clone:

LBI2D11

Conjugation:

Unconjugated

Gene name:

Homo sapiens ring finger protein 1 (RING1), mRNA.

Symbol:

RING1

Pathway:

Request info at info@sobekbio.com

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:250

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com