Product overview:

Carrier-free (BSA/glycerol-free) TGM2 mouse monoclonal antibody,clone LBI1A3

Field of research:

Huntington's disease

Summary:

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC

Species reactivity:

Human

Host:

Mouse

Target:

TGM2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TGM2 (NP_004604) produced in HEK293T cell.

Clone:

LBI1A3

Conjugation:

Unconjugated

Gene name:

Homo sapiens transglutaminase 2 (TGM2), transcript variant 1, mRNA.

Symbol:

TGM2

Pathway:

Huntington's disease

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500, IHC 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com