Product overview:

Carrier-free (BSA/glycerol-free) DACT1 mouse monoclonal antibody,clone LBI10F12

Field of research:

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Summary:

The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Alternative names:

DAPPER; DAPPER1; DPR1; FRODO; HDPR1; THYEX3

Species reactivity:

Human

Host:

Mouse

Target:

DACT1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 289-555 of human DACT1(NP_057735) produced in E.coli.

Clone:

LBI10F12

Conjugation:

Unconjugated

Gene name:

Homo sapiens dishevelled binding antagonist of beta catenin 1 (DACT1), transcript variant 1, mRNA.

Symbol:

DACT1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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