Product overview:

Carrier-free (BSA/glycerol-free) TSN mouse monoclonal antibody,clone LBI1B5

Field of research:

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Summary:

This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Alternative names:

BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TSN

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-51 of human TSN(NP_004613) produced in E.coli.

Clone:

LBI1B5

Conjugation:

Unconjugated

Gene name:

Homo sapiens translin (TSN), transcript variant 1, mRNA.

Symbol:

TSN

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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