Product overview:

Carrier-free (BSA/glycerol-free) TRIM56 mouse monoclonal antibody,clone LBI8E12

Field of research:

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Summary:

E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA. [UniProtKB/Swiss-Prot Function]

Alternative names:

RNF109

Species reactivity:

Human

Host:

Mouse

Target:

TRIM56

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 311-554 of human TRIM56(NP_112223) produced in E.coli.

Clone:

LBI8E12

Conjugation:

Unconjugated

Gene name:

Homo sapiens tripartite motif containing 56 (TRIM56), mRNA.

Symbol:

TRIM56

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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