Product overview:

Carrier-free (BSA/glycerol-free) CD34 mouse monoclonal antibody,clone LBI8F11

Field of research:

Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Summary:

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. [UniProtKB/Swiss-Prot Function]

Alternative names:

CD34 antigen; CD34 molecule; hematopoietic progenitor cell antigen CD34; OTTHUMP00000034733; OTTHUMP00000034734

Species reactivity:

Human

Host:

Mouse

Target:

CD34

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 312-385 of human CD34(NP_001020280) produced in E.coli.

Clone:

LBI8F11

Conjugation:

Unconjugated

Gene name:

Homo sapiens CD34 molecule (CD34), transcript variant 1, mRNA.

Symbol:

CD34

Pathway:

Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Function:

Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com