Product overview:

Carrier-free (BSA/glycerol-free) ICOSLG mouse monoclonal antibody, clone LBI2G10

Field of research:

Cell adhesion molecules (CAMs)

Summary:

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. [UniProtKB/Swiss-Prot Function]

Alternative names:

B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS

Species reactivity:

Human

Host:

Mouse

Target:

ICOSLG

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ICOSLG (NP_056074) produced in HEK293T cell.

Clone:

LBI2G10

Conjugation:

Unconjugated

Gene name:

Homo sapiens inducible T cell costimulator ligand (ICOSLG), transcript variant 1, mRNA.

Symbol:

ICOSLG

Pathway:

Cell adhesion molecules (CAMs)

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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