Product overview:

Carrier-free (BSA/glycerol-free) EXOSC1 mouse monoclonal antibody, clone LBI4B7

Field of research:

RNA degradation

Summary:

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq, Jul 2008]

Alternative names:

CGI-108; CSL4; Csl4p; hCsl4p; p13; SKI4; Ski4p

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

EXOSC1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human EXOSC1 (NP_057130) produced in E.coli.

Clone:

LBI4B7

Conjugation:

Unconjugated

Gene name:

Homo sapiens exosome component 1 (EXOSC1), transcript variant 1, mRNA.

Symbol:

EXOSC1

Pathway:

RNA degradation

Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com