Product overview:

Carrier-free (BSA/glycerol-free) MAVS mouse monoclonal antibody, clone LBI9C7

Field of research:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Summary:

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Alternative names:

CARDIF; IPS-1; IPS1; VISA

Species reactivity:

Human

Host:

Mouse

Target:

MAVS

Isotype:

IgG3

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-247 of human MAVS(NP_065797) produced in E.coli.

Clone:

LBI9C7

Conjugation:

Unconjugated

Gene name:

Homo sapiens mitochondrial antiviral signaling protein (MAVS), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

Symbol:

MAVS

Pathway:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com