Product overview:

Carrier-free (BSA/glycerol-free) ASB2 mouse monoclonal antibody, clone LBI4C2

Field of research:

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Summary:

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Alternative names:

ASB-2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ASB2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-300 of human ASB2(NP_057234) produced in E.coli.

Clone:

LBI4C2

Conjugation:

Unconjugated

Gene name:

Homo sapiens ankyrin repeat and SOCS box containing 2 (ASB2), transcript variant 2, mRNA.

Symbol:

ASB2

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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