Product overview:

Carrier-free (BSA/glycerol-free) CD22 mouse monoclonal antibody, clone LBI2A4

Field of research:

B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Summary:

Predominantly monomer of isoform CD22-beta. Also found as heterodimer of isoform CD22-beta and a shorter isoform. Interacts with PTPN6/SHP-1, LYN, SYK, PIK3R1/PIK3R2 and PLCG1 upon phosphorylation. Interacts with GRB2, INPP5D and SHC1 upon phosphorylation (By similarity). May form a complex with INPP5D/SHIP, GRB2 and SHC1. [UniProtKB/Swiss-Prot Function]

Alternative names:

SIGLEC-2; SIGLEC2

Species reactivity:

Human

Host:

Mouse

Target:

CD22

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 707-847 of human CD22(NP_001762) produced in E.coli.

Clone:

LBI2A4

Conjugation:

Unconjugated

Gene name:

Homo sapiens CD22 molecule (CD22), transcript variant 1, mRNA.

Symbol:

CD22

Pathway:

B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com