Product overview:

Carrier-free (BSA/glycerol-free) NDUFB11 mouse monoclonal antibody, clone LBI2E10

Field of research:

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Summary:

NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 [PubMed 12381726]). [supplied by OMIM, Feb 2009]. Transcript Variant: This variant (2) uses a different splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter C-terminus when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY359056.1, BE781599.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025084, ERS025087 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

Alternative names:

CI-ESSS; ESSS; Np15; NP17.3; P17.3

Species reactivity:

Human

Host:

Mouse

Target:

NDUFB11

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 30-163 of human NDUFB11(NP_061929) produced in E.coli.

Clone:

LBI2E10

Conjugation:

Unconjugated

Gene name:

Homo sapiens NADH:ubiquinone oxidoreductase subunit B11 (NDUFB11), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

Symbol:

NDUFB11

Pathway:

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Function:

Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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