Product overview:

Carrier-free (BSA/glycerol-free) DEDD mouse monoclonal antibody,clone LBI7C9

Field of research:

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Summary:

This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

CASP8IP1; DEDD1; DEFT; FLDED1; KE05

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DEDD

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-318 of human DEDD (NP_127491) produced in E.coli.

Clone:

LBI7C9

Conjugation:

Unconjugated

Gene name:

Homo sapiens death effector domain containing (DEDD), transcript variant 1, mRNA.

Symbol:

DEDD

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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