Product overview:

Carrier-free (BSA/glycerol-free) CCT4 mouse monoclonal antibody,clone LBI5E5

Field of research:

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Summary:

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]). [supplied by OMIM, Mar 2008]

Alternative names:

CCT-DELTA; Cctd; SRB

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CCT4

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human CCT4 (NP_006421) produced in E.coli.

Clone:

LBI5E5

Conjugation:

Unconjugated

Gene name:

Homo sapiens chaperonin containing TCP1 subunit 4 (CCT4), transcript variant 1, mRNA.

Symbol:

CCT4

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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