Product overview:

Carrier-free (BSA/glycerol-free) VWF mouse monoclonal antibody, clone LBI1D4

Field of research:

Complement and coagulation cascades, ECM-receptor interaction, Focal adhesion

Summary:

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Alternative names:

F8VWF; VWD

Species reactivity:

Human

Host:

Mouse

Target:

VWF

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 764-1263 of human VWF (NP_000543) produced in SF9 cell.

Clone:

LBI1D4

Conjugation:

Unconjugated

Gene name:

Homo sapiens von Willebrand factor (VWF), mRNA.

Symbol:

VWF

Pathway:

Complement and coagulation cascades, ECM-receptor interaction, Focal adhesion

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com