Product overview:

Carrier-free (BSA/glycerol-free) NUMB mouse monoclonal antibody, clone LBI2B9

Field of research:

Notch signaling pathway

Summary:

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

C14orf41; c14_5527; S171

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NUMB

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-365 of human NUMB (NP_001005744) produced in E.coli.

Clone:

LBI2B9

Conjugation:

Unconjugated

Gene name:

Homo sapiens NUMB endocytic adaptor protein (NUMB), transcript variant 2, mRNA.

Symbol:

NUMB

Pathway:

Notch signaling pathway

Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com