Product overview:

Carrier-free (BSA/glycerol-free) DOCK8 mouse monoclonal antibody, clone LBI8D9

Field of research:

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Summary:

This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

Alternative names:

HEL-205; MRD2; ZIR8

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DOCK8

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 84-405 of human DOCK8 (NP_982272) produced in E.coli.

Clone:

LBI8D9

Conjugation:

Unconjugated

Gene name:

Homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 1, mRNA.

Symbol:

DOCK8

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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