Product overview:

Carrier-free (BSA/glycerol-free) KLK8 mouse monoclonal antibody, clone LBI3A12

Field of research:

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Summary:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Alternative names:

HNP; NP; NRPN; PRSS19; TADG14

Species reactivity:

Human

Host:

Mouse

Target:

KLK8

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 33-260 of human KLK8 (NP_009127) produced in E.coli.

Clone:

LBI3A12

Conjugation:

Unconjugated

Gene name:

Homo sapiens kallikrein related peptidase 8 (KLK8), transcript variant 1, mRNA.

Symbol:

KLK8

Pathway:

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Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com