Product overview:

Carrier-free (BSA/glycerol-free) HSPD1 mouse monoclonal antibody,clone LBI6F11

Field of research:

RNA degradation, Type I diabetes mellitus

Summary:

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun

Alternative names:

CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

HSPD1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HSPD1 (NP_955472) produced in E.coli.

Clone:

LBI6F11

Conjugation:

Unconjugated

Gene name:

Homo sapiens heat shock protein family D (Hsp60) member 1 (HSPD1), transcript variant 2, mRNA; nuclear gene for mitochondrial product.

Symbol:

HSPD1

Pathway:

RNA degradation, Type I diabetes mellitus

Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com