Product overview:

Carrier-free (BSA/glycerol-free) CUL4B mouse monoclonal antibody, clone LBI7G10

Field of research:

Nucleotide excision repair, Ubiquitin mediated proteolysis

Summary:

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CUL4B

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-300 of human CUL4B (NP_003579) produced in E.coli.

Clone:

LBI7G10

Conjugation:

Unconjugated

Gene name:

Homo sapiens cullin 4B (CUL4B), transcript variant 1, mRNA.

Symbol:

CUL4B

Pathway:

Nucleotide excision repair, Ubiquitin mediated proteolysis

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com