Product overview:

Carrier-free (glycerol/BSA-free) SCP2 mouse monoclonal antibody, clone LBI3F5

Field of research:

Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

Summary:

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Aug 2010]

Alternative names:

NLTP; NSL-TP; SCOX; SCP-2; SCP-CHI; SCP-X; SCPX

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SCP2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SCP2(NP_002970) produced in HEK293T cell

Clone:

LBI3F5

Conjugation:

Unconjugated

Gene name:

Homo sapiens sterol carrier protein 2 (SCP2), transcript variant 1, mRNA.

Symbol:

SCP2

Pathway:

Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:4000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com