Product overview:

Carrier-free (BSA/glycerol-free) FGG mouse monoclonal antibody, clone LBI4G2

Field of research:

Complement and coagulation cascades

Summary:

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul

Alternative names:

fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide

Species reactivity:

Human

Host:

Mouse

Target:

FGG

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human FGG(NP_000500) produced in HEK293T cell.

Clone:

LBI4G2

Conjugation:

Unconjugated

Gene name:

Homo sapiens fibrinogen gamma chain (FGG), transcript variant gamma, mRNA.

Symbol:

FGG

Pathway:

Complement and coagulation cascades

Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:4000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com