Product overview:

Carrier-free (BSA/glycerol-free) HSD17B4 mouse monoclonal antibody, clone LBI3C5

Field of research:

Metabolic pathways, Primary bile acid biosynthesis

Summary:

The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq, Jul 2008]

Alternative names:

DBP; MFE-2; MPF-2; PRLTS1; SDR8C1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HSD17B4

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HSD17B4(NP_000405) produced in HEK293T cell.

Clone:

LBI3C5

Conjugation:

Unconjugated

Gene name:

Homo sapiens hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4), transcript variant 2, mRNA.

Symbol:

HSD17B4

Pathway:

Metabolic pathways, Primary bile acid biosynthesis

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:4000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com