Product overview:

Carrier-free (BSA/glycerol-free) RAPGEF1 mouse monoclonal antibody, clone LBI3H5

Field of research:

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Summary:

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Alternative names:

C3G; GRF2

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

RAPGEF1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human RAPGEF1(NP_941372) produced in HEK293T cell.

Clone:

LBI3H5

Conjugation:

Unconjugated

Gene name:

Homo sapiens Rap guanine nucleotide exchange factor 1 (RAPGEF1), transcript variant 2, mRNA.

Symbol:

RAPGEF1

Pathway:

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:400~4000, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com