Product overview:

Carrier-free (BSA/glycerol-free) MMP13 mouse monoclonal antibody, clone LBI4B7

Field of research:

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Summary:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Alternative names:

CLG3; MANDP1; MDST; MMP-13

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

MMP13

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 104-471 of human MMP13(NP_002418) produced in HEK293T cell.

Clone:

LBI4B7

Conjugation:

Unconjugated

Gene name:

Homo sapiens matrix metallopeptidase 13 (MMP13), mRNA.

Symbol:

MMP13

Pathway:

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Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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