Product overview:

Carrier-free (BSA/glycerol-free) ARG2 mouse monoclonal antibody, clone LBI1F6

Field of research:

Arginine and proline metabolism, Metabolic pathways

Summary:

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]

Alternative names:

arginase; arginase 2; kidney arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; nonhepatic arginase; type II

Species reactivity:

Human

Host:

Mouse

Target:

ARG2

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human ARG2(NP_001163) produced in HEK293T cell.

Clone:

LBI1F6

Conjugation:

Unconjugated

Gene name:

Homo sapiens arginase 2 (ARG2), mRNA; nuclear gene for mitochondrial product.

Symbol:

ARG2

Pathway:

Arginine and proline metabolism, Metabolic pathways

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:4000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com