Product overview:

Carrier-free (BSA/glycerol-free) DDX58 mouse monoclonal antibody, clone LBI7D5

Field of research:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Summary:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]

Alternative names:

RIG-I; RIGI; RLR-1

Species reactivity:

Human

Host:

Mouse

Target:

DDX58

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human DDX58(NP_055129) produced in HEK293T cell.

Clone:

LBI7D5

Conjugation:

Unconjugated

Gene name:

Homo sapiens DExD/H-box helicase 58 (DDX58), transcript variant 1, mRNA.

Symbol:

DDX58

Pathway:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:1000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com