Product overview:

Carrier-free (BSA/glycerol-free) CA12 mouse monoclonal antibody, clone LBI3F1

Field of research:

Nitrogen metabolism

Summary:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

CAXII; HsT18816

Species reactivity:

Human

Host:

Mouse

Target:

CA12

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CA12(NP_001209) produced in HEK293T cell.

Clone:

LBI3F1

Conjugation:

Unconjugated

Gene name:

Homo sapiens carbonic anhydrase 12 (CA12), transcript variant 1, mRNA.

Symbol:

CA12

Pathway:

Nitrogen metabolism

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, FLOW 1:50

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com