Product overview:

Carrier-free (BSA/glycerol-free) ETS2 mouse monoclonal antibody, clone LBI2A3

Field of research:

Dorso-ventral axis formation

Summary:

ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]). [supplied by OMIM]

Alternative names:

ETS2IT1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

ETS2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 90-349 of human ETS2(NP_005230) produced in E.coli.

Clone:

LBI2A3

Conjugation:

Unconjugated

Gene name:

Homo sapiens ETS proto-oncogene 2, transcription factor (ETS2), transcript variant 1, mRNA.

Symbol:

ETS2

Pathway:

Dorso-ventral axis formation

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com