Product overview:

Carrier-free (BSA/glycerol-free) SRY mouse monoclonal antibody,clone LBI3C8

Field of research:

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Summary:

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]

Alternative names:

SRXX1; SRXY1; TDF; TDY

Species reactivity:

Human

Host:

Mouse

Target:

SRY

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SRY(NP_003131) produced in E.coli.

Clone:

LBI3C8

Conjugation:

Unconjugated

Gene name:

Homo sapiens sex determining region Y (SRY), mRNA.

Symbol:

SRY

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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