Product overview:

Carrier-free (BSA/glycerol-free) ASGR2 mouse monoclonal antibody, clone LBI2A12

Field of research:

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Summary:

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Alternative names:

ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2

Species reactivity:

Human

Host:

Mouse

Target:

ASGR2

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human ASGR2 (NP_001172) produced in HEK293T cell.

Clone:

LBI2A12

Conjugation:

Unconjugated

Gene name:

Homo sapiens asialoglycoprotein receptor 2 (ASGR2), transcript variant 1, mRNA.

Symbol:

ASGR2

Pathway:

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Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:4000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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