Product overview:

Carrier-free (BSA/glycerol-free) ATRIP mouse monoclonal antibody, clone LBI1G6

Field of research:

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Summary:

The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740

Species reactivity:

Human

Host:

Mouse

Target:

ATRIP

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 42-309 of human ATRIP(NP_569055) produced in E.coli.

Clone:

LBI1G6

Conjugation:

Unconjugated

Gene name:

Homo sapiens ATR interacting protein (ATRIP), transcript variant 1, mRNA.

Symbol:

ATRIP

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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