Product overview:

Carrier-free (BSA/glycerol-free) CAPN2 mouse monoclonal antibody, clone LBI3G1

Field of research:

Alzheimer's disease, Apoptosis, Focal adhesion

Summary:

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Alternative names:

CANP2; CANPL2; CANPml; mCANP

Species reactivity:

Human, Mouse, Rat, Dog

Host:

Mouse

Target:

CAPN2

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human CAPN2(NP_001739) produced in HEK293T cell.

Clone:

LBI3G1

Conjugation:

Unconjugated

Gene name:

Homo sapiens calpain 2 (CAPN2), transcript variant 1, mRNA.

Symbol:

CAPN2

Pathway:

Alzheimer's disease, Apoptosis, Focal adhesion

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com