Product overview:

Carrier-free (BSA/glycerol-free) PSMA4 mouse monoclonal antibody, clone LBI5D8

Field of research:

Proteasome

Summary:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternative names:

HC9; HsT17706; PSC9

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

PSMA4

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PSMA4(NP_002780) produced in HEK293T cell.

Clone:

LBI5D8

Conjugation:

Unconjugated

Gene name:

Homo sapiens proteasome 20S subunit alpha 4 (PSMA4), transcript variant 1, mRNA.

Symbol:

PSMA4

Pathway:

Proteasome

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com