Product info:

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants.

Alternative names:

ZFYVE1; DFCP1; PPP1R172; SR3; TAFF1; ZNFN2A1

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

Endoplasmic reticulum, Golgi apparatus, Golgi stack

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ZFYVE1 (NP_067083.1).

Positive control:

293T

AA Sequence:

MSAQTSPAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKPGHVPYCDLCKGLSGHLPGVRQRAIVRCQTCKINLCLECQKRTHSGGNKRRHPVTVYNVSNLQESLEAEEMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPTQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFL

Purification:

Affinity purification

Molecular weight:

Calculated MW: 40kDa/85kDa/87kDa Observed MW: 87kDa

Form:

Liquid

Applications:

WB (Homo sapiens, Mus musculus) IF (Homo sapiens) IHC (Homo sapiens) Co-IP (Mus musculus)

Dilution:

WB 1:500 - 1:2000 IF 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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