Product info:

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions.

Alternative names:

C/EBP-beta; IL6DBP; NF-IL6; TCF5; CEBP beta; CEBPB

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cytoplasm, Nucleus

Isotype:

IgG

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human C/EBPB (NP_005185.2).

Positive control:

MCF7, Mouse liver, Rat liver

AA Sequence:

GALHPGCFAPLHPPPPPPPPPAELKAEPGFEPADCKRKEEAGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAKAPPTACYA

Purification:

Affinity purification

Molecular weight:

Calculated MW: 15kDa/33kDa/36kDa Observed MW: 42KDa/46KDa

Form:

Liquid

Applications:

WB (Mus musculus, Rattus norvegicus)

Dilution:

WB 1:500 - 1:1000 IHC 1:20 - 1:100

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com