Product info:

Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV, hepatitis A virus (HAV and yellow fever virus (YFV in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.

Alternative names:

ISG20; CD25; HEM45

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cajal body, Cytoplasm, Nucleus, nucleolus

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ISG20 (NP_002192.2).

Positive control:

Raji, A-549, MCF7, Mouse spleen, Rat spleen

AA Sequence:

MAGSREVVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPF

Purification:

Affinity purification

Molecular weight:

Calculated MW: 9kDa/20kDa Observed MW: 20kDa

Form:

Liquid

Applications:

IHC (Homo sapiens) WB (Homo sapiens)

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com