Product info:

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.

Alternative names:

SOX30

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Nucleus

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of mouse SOX30 (NP_775560.1).

Positive control:

U-87MG, BxPC-3, SGC-7901, Mouse pancreas, Mouse stomach, Rat brain

AA Sequence:

MERARPEPPPPPPPPPRQPPRPTPPRPLRPAPPAQPVEAATFRAAAAERSQSPSAQATAAMAAVASSCGEAAAAGAQAAGTRRLLQVKPEQVLLLPPGGPGVPPAPDEGAAAAAAAAAAAASSAQARLLQLRPELLLLPPQSAADGGPCR

Purification:

Affinity purification

Molecular weight:

Calculated MW: 83kDa Observed MW: 110kDa

Form:

Liquid

Applications:

IHC (Mus musculus) WB (Mus musculus) IP (Mus musculus) IF (Mus musculus)

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com