Product info:

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.

Alternative names:

VLDLR; CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLRCH

Species reactivity:

Human, Mouse

Host:

Rabbit

Cellular localisation:

Membrane, Single-pass type I membrane protein, clathrin-coated pit

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 20-210 of human VLDLR (NP_001018066.1).

Positive control:

THP-1, Mouse lung, Mouse ovary

AA Sequence:

RESGATGTGRKAKCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISW

Purification:

Affinity purification

Molecular weight:

Calculated MW: 93kDa/96kDa Observed MW: 110kDa

Form:

Liquid

Applications:

IHC (Gallus gallus)

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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