Product info:

This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Alternative names:

GJA4; CX37

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

Cell junction, Cell membrane, Multi-pass membrane protein, gap junction

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 229-333 of human GJA4 (NP_002051.2).

Positive control:

SW620, BT-474, 293T, NCI-H460

AA Sequence:

VHLLCRCLSRGMRARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV

Purification:

Affinity purification

Molecular weight:

Calculated MW: 37kDa Observed MW: 43kDa

Form:

Liquid

Applications:

IF (Homo sapiens)

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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