Product info:

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names:

MYH2; IBM3; MYH2A; MYHSA2; MYHas8; MYPOP; MyHC-2A; MyHC-IIa; myosin-2

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Cytoplasm, myofibril

Isotype:

IgG

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 550-650 of human MYH2 (NP_001093582.1).

Positive control:

Mouse skeletal muscle, Rat skeletal muscle

AA Sequence:

SFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSF

Purification:

Affinity purification

Molecular weight:

Calculated MW: 79kDa/223kDa Observed MW: 250KDa

Form:

Liquid

Applications:

WB (Sus scrofa)

Dilution:

WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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