Product info:

Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1 and transferrin receptor (TFR; internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.

Alternative names:

EPS15L1; EPS15R

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

Cell membrane, Membrane, Nucleus, Peripheral membrane protein, coated pit

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 475-754 of human EPS15L1 (NP_001245304.1).

Positive control:

MCF7, HepG2, HeLa, BxPC-3, U-251MG

AA Sequence:

QMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKVKVHL

Purification:

Affinity purification

Molecular weight:

Calculated MW: 66kDa/83kDa/94kDa/99kDa Observed MW: 110kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com