Product info:

Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3. Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs (By similarity. Essential for male fertility and spermatogenesis (By similarity. Required for meiosis prophase I progression in male but not in female germ cells (By similarity.

Alternative names:

ZCWPW1; ZCW1

Species reactivity:

Human, Mouse

Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 389-648 of human ZCWPW1 (NP_060454.3).

Positive control:

OVCAR3, SKOV3, mouse testis

AA Sequence:

VMKKRRNDCSQKLGVALMMAQEAEQISIQERVNLFGFWSRFNGSNSNGERKDLQLSGLNSPGSCLEKKEKEEELEKEEGEKTDPILPIRKRVKIQTQKTKPRGLGGDAGTADGRGRTLQRKIMKRSLGRKSTAPPAPRMGRKEGQGNSDSDQPGPKKKFKAPQSKALAASFSEGKEVRTVPKNLGLSACKGACPSSAKEEPRHREPLTQEAGSVPLEDEASSDLDLEQLMEDVGRELGQSGELQHSNSDGEDFPVALFGK

Purification:

Affinity purification

Molecular weight:

Calculated MW: 45kDa/52kDa/53kDa/59kDa/72kDa Observed MW: 72kDa

Form:

Liquid

Applications:

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Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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