Product info:

This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.

Alternative names:

SUMO4; IDDM5; SMT3H4; SUMO-4; dJ281H8.4

Species reactivity:

Human, Mouse

Host:

Rabbit

Cellular localisation:

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Isotype:

IgG

Immunogen:

A synthetic peptide of human SUMO4

Positive control:

Jurkat, MCF7

AA Sequence:

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Purification:

Affinity purification

Molecular weight:

Calculated MW: 10kDa Observed MW: 18kDa

Form:

Liquid

Applications:

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Dilution:

WB 1:1000 - 1:2000 IHC 1:100 - 1:300

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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