Product info:

Mediates the electrogenic exchange of Ca(2+ against Na(+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+ levels and Ca(2+-dependent cellular processes. Contributes to cellular Ca(2+ homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+ levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+ and Na(+ excretion.

Alternative names:

SLC8A2; NCX2

Species reactivity:

Human

Host:

Rabbit

Cellular localisation:

Basolateral cell membrane, Cell membrane, Cell projection, Multi-pass membrane protein, Perikaryon, dendrite, dendritic spine

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1).

Positive control:

U-87MG, 293T

AA Sequence:

LMTGAGNVLRRHAADASRRAAPAEGAGEDEDDGASRIFFEPSLYHCLENCGSVLLSVTCQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGT

Purification:

Affinity purification

Molecular weight:

Calculated MW: 100kDa Observed MW: 100kDa

Form:

Liquid

Applications:

Request info at info@sobekbio.com

Dilution:

WB 1:500 - 1:2000

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com